Correlation between serum gastrin concentration and rat stomach histidine decarboxylase activity
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منابع مشابه
Effect of hydrocortisone on histidine decarboxylase activity in rat stomach.
Hydrocortisone-stimulated synthesis of histidine decarboxylase (EC 4.1.1.22) was studied in rat stomach. Single or daily administration of hydrocortisone increased the histidine decarboxylase activity but not the histamine content in the fundic glands of stomachs from fed and fasted rats with or without adrenalectomy, and also in those from adrenalectomized fasted rats with concomitant treatmen...
متن کاملImmunolocalization of gastrin-dependent histidine decarboxylase activity in rat gastric mucosa during feeding.
The localization of histidine decarboxylase (HDC) activity in the enterochromaffin-like (ECL) cells of the oxyntic mucosa was studied during fasting and refeeding using monoclonal (CURE no. 44178) and polyclonal (CURE no. 94211) antibodies directed against the COOH terminus of HDC (HDC-CT). Changes in HDC immunostaining were correlated with mucosal HDC enzyme activity. Immunoneutralization of c...
متن کاملHistidine decarboxylase. Purification from fetal rat liver, immunologic properties, and histochemical localization in brain and stomach.
Histidine decarboxylase from fetal rat liver was purified to near-homogeneity. The purified enzyme has a molecular weight of 210,000, and appears to contain two subunits with molecular weights of 145,000 and 66,000, respectively. The enzyme is inhibited by heavy metals such as Hg2+ and Zn2+ and sulfhydryl-reactive compounds such as 5,5'-dithiobis-2-nitrobenzoic acid. The enzyme is partially dep...
متن کاملIntracisternal TRH analog increases gastrin release and corpus histidine decarboxylase activity in rats.
Thyrotropin-releasing hormone (TRH) acts in brain stem nuclei to induce vagally mediated stimulation of gastric secretion. The effects of intracisternal injection of the TRH analog RX-77368 on plasma gastrin levels and corpus histidine decarboxylase (HDC) activity were studied in 48-h fasted conscious rats. RX-77368 (25-100 ng) increased plasma gastrin levels by threefold at 30 min, which remai...
متن کاملElevation of histidine decarboxylase activity in skeletal muscles and stomach in mice by stress and exercise.
The effects of different types of stress (water bathing, cold, restraint, and prolonged walking) on histidine decarboxylase (HDC) activity in masseter, quadriceps femoris, and pectoralis superficial muscles, and in the stomach were examined in mice. All of these stresses elevated gastric HDC activity. Although water bathing, in which muscle activity was slight, was sufficiently stressful to pro...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1974
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1974.sp010763